• search
Country
CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Viral Vectors Services

Viral Vectors Services

We deliver high quality research grade Lentiviral (LV) and Adeno associated viral (AAV) vectors to support preclinical cell and gene therapy (CGT) product development programs.

The most effective method of gene transfer for modifying specific cell types or tissues is viral vector, which can be used for expressing therapeutic genes.

We deliver high quality research grade Lentiviral (LV) and Adeno associated viral (AAV) vectors to support preclinical cell and gene therapy (CGT) product development programs.

Speak to our experts

Adeno-associated Viral (AAV) Vector

Plasmid production and characterization

  • GMP like (packaging, helper and transfer plasmids)
  • Digestion and sequencing

Upstream process development

  • Helper free triple transfection
  • HEK293 suspension or adherent
  • Transfection (PEI or other methods)
  • Shake flask, wave bioreactors and stirred-tank reactor

Purification

  • Lysis, clarification and concentration, Benzonase, TFF
  • Ultracentrifuge or Chromatography (IEX, AEX, affinity, SEC)
  • Concentration and buffer exchange, TFF and sterile filtration

QC and release

  • General or physical properties
  • Identity
  • Safety
  • Purity
  • Strength
  • Potency

Lentiviral (LV) Vector

Plasmid production and characterization

  • GMP like (Gag-pol, VSVG, Rev and Transfer plasmids)
  • Digestion and sequencing

Upstream process development

  • 3rd Generation system
  • HEK293 suspension or adherent
  • Transfection (PEI or other methods)
  • Shake flask, wave bioreactors and stirred-tank reactor

Purification

  • Clarification and concentration, Benzonase, TFF
  • Ultracentrifuge or chromatography (IEX, AEX, affinity, SEC)
  • Concentration and buffer exchange, TFF and sterile filtration

QC and release

  • General or Physical properties
  • Identity
  • Safety
  • Purity
  • Strength
  • Potency

Why Aurigene Pharmaceutical Services?

Customized vector construction

State-of-the-art facilities

Regulatory audits and compliance to statutory norms

Team of scientists with extensive experience in viral vector generation

Virtual Tour

 

Contact Us

Country
CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
resourceMainImage

JUNE 28, 2022

Neoantigen Specific T cells For Cancer Immunotherapy

Neoantigen specific T cells for cellular cancer immunotherapy An effective anti-tumor immune response in human is marked by presence of T cells reactive against neoantigens. Neoantigens are HLA-bound unique peptides arise from tumor-specific somatic mutations. Neoantigens are highly immunogenic because they are not present in normal tissues and hence...

Read More
resourceMainImage

Building successful long-term partnerships with CDMOs from early drug discovery through commercialization

Building successful long-term partnerships with CDMOs from early drug discovery through commercialization Maximizing efficiency in drug research, development, and manufacturing is crucial for turning new innovations into therapeutic and financial benefits. Over the past couple of decades, pharmaceutical companies have increasingly turned to contr...

Read More
resourceMainImage

Technology meets sustainability - How a complex API development process goes green

We are always looking for ways to enhance the sustainability of our products and services. Our team successfully developed a scalable manufacturing process for the API product of one of our Biotech clients using eco-friendly manufacturing technologies. Read the case study to learn more. ...

Read More

Alternate end-game strategies towards Nirmatrelvir synthesis: Defining a continuous flow process for the preparation of an anti-COVID drug

2023

Scalable alternate end-game strategies for the synthesis of the anti-COVID drug molecule Nirmatrelvir (1,PF-07321332) have been described. The first involves a direct synthesis of 1 via amidation of the carboxylic acid 7 (suitably activated as a mixed anhydride with either pivaloyl chloride or T3P) with the ...

Read More
View All
×

You are about to leave Aurigene Pharmaceutical Services and affiliates website. Aurigene Pharmaceutical Services assumes no responsibility for the information presented on the external website or any further links from such sites. These links are presented to you only as a convenience, and the inclusion of any link does not imply endorsement by Aurigene Pharmaceutical Services.

If you wish to continue to this external website, click Proceed.

ProceedBack