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Viral Vectors Services Viral Vectors Services

Viral Vectors Services

We deliver high quality research grade Lentiviral (LV) and Adeno associated viral (AAV) vectors to support preclinical cell and gene therapy (CGT) product development programs.

The most effective method of gene transfer for modifying specific cell types or tissues is viral vector, which can be used for expressing therapeutic genes. 

We deliver high quality research grade Lentiviral (LV) and Adeno associated viral (AAV) vectors to support preclinical cell and gene therapy (CGT) product development programs.

Speak to our experts

Adeno-associated Viral (AAV) Vector

Plasmid production and characterization

  • GMP like (packaging, helper and transfer plasmids)
  • Digestion and sequencing

Upstream process development

  • Helper free triple transfection
  • HEK293 suspension or adherent
  • Transfection (PEI or other methods)
  • Shake flask, wave bioreactors and stirred-tank reactor

Purification

  • Lysis, clarification and concentration, Benzonase, TFF
  • Ultracentrifuge or Chromatography (IEX, AEX, affinity, SEC)
  • Concentration and buffer exchange, TFF and sterile filtration

QC and release

  • General or physical properties
  • Identity
  • Safety
  • Purity
  • Strength
  • Potency

Lentiviral (LV) Vector

Plasmid production and characterization

  • GMP like (Gag-pol, VSVG, Rev and Transfer plasmids)
  • Digestion and sequencing

Upstream process development

  • 3rd Generation system
  • HEK293 suspension or adherent
  • Transfection (PEI or other methods)
  • Shake flask, wave bioreactors and stirred-tank reactor

Purification

  • Clarification and concentration, Benzonase, TFF
  • Ultracentrifuge or chromatography (IEX, AEX, affinity, SEC)
  • Concentration and buffer exchange, TFF and sterile filtration

QC and release

  • General or Physical properties
  • Identity
  • Safety
  • Purity
  • Strength
  • Potency

Why Aurigene Pharmaceutical Services?

Customized vector construction

State-of-the-art facilities

Regulatory audits and compliance to statutory norms

Team of scientists with extensive experience in viral vector generation

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