2023
Aurigene Pharmaceutical Services to expand biologics CDMO capacity with a new biomanufacturing facility
Aurigene is investing $40m Mn USD in an R&D and pilot scale facility as a first step towards a series of strategic investments. Complemented by exclusive access to large-scale GMP commercial manufacturing capacity including fill-finish.
Read MoreAurigene Pharmaceutical Services to invest Rs 330 crore in Genome Valley
Aurigene Pharmaceutical Services, a contract research, development, and manufacturing services organisation and a step-down subsidiary of Dr Reddy's Laboratories, has decided to establish a development and manufacturing facility focused on niche areas like therapeutic proteins, antibodies, and viral vectors in Hyderabad.
Read More2022
Aurigene Pharmaceutical Services Launches its New Branding at CPHI North America
Aurigene has been established as a wholly-owned subsidiary of Dr. Reddy’s through the merger of Aurigene Discovery Services and Dr. Reddy’s Custom Pharma Services (CPS). The launch of the brand happened during the pandemic and it is therefore the first opportunity for the team to exhibit the new brand to its customers.
Read MoreAurigene Pharmaceutical Services, Dr. Reddy's Laboratories and DNDi to explore joint opportunities to develop affordable and life-saving new drugs for Neglected Tropical Diseases
Potential partnership to explore new therapeutic solutions and serve unmet needs of patients in Neglected Tropical Diseases in LMICs and beyond.
Read More2021
DeepMatter to trial its DigitalGlassware® platform with Aurigene Pharmaceutical Services
DeepMatter Group Plc (AIM: DMTR, “Deepmatter”, the “Group”), the international digital chemistry data company, has signed a trials agreement with Aurigene Pharmaceutical Services Limited (“Aurigene Pharmaceutical Services”), based in Hyderabad, India, to supply its DigitalGlassware® platform.
Read MoreAurigene Pharmaceutical Services Limited (APSL) invests in adding Large Molecule Discovery and Development Services
Aurigene Pharmaceutical Services Limited, a wholly-owned subsidiary of Dr. Reddy’s expands its existing discovery and development capacities with the inauguration of a biotherapeutics discovery facility in Hyderabad, India.
Read MoreAurigene Pharmaceutical Services is
a leading CRO/CDMO
that provides contract research, development and manufacturing services
Resource
Drug Development
A Brief Introduction to Click Chemistry and Bioorthogonal Chemistry
AUGUST 23, 2023
Drug Development
“Bathtub Chemistry” - Necessity and Aspects of Process Research
MAY 19, 2023
Business Continuity
The importance of business continuity planning in CRDMO industry
APRIL 24, 2023
Large Molecule Discovery Services
Neoantigen Specific T cells For Cancer Immunotherapy
JUNE 28, 2022
Pharmaceutical Services
Oligonucleotide as a novel class of therapeutic modality
JULY 02, 2021
Studies and Research
The influence of formulation development and its route of administration
JANUARY 04, 2021
Development and Manufacturing
Application and Manufacturing of High Potent Active Pharmaceutical Ingredient (HPAPI)
JANUARY 04, 2021
Development and Manufacturing
Application of mPEGs in Drug Discovery and Development
JANUARY 04, 2021
Development and Manufacturing
Emerging Trends in Solid State Phase Peptide Synthesis
FEBRUARY 23, 2021
Peptide Synthesis
Carbohydrate
Early Phase development
Safety assessment
Steroids
Anti-Infective Drug Discovery
Manufacturing an activated mPEG derivative
Familiarization, process optimization and non- GMP manufacturing & supply of 3.0 kg of HPAPI product
Solid dispersion development to enhance solubility and oral bioavailability for rodent toxicology studies
Delivering 3 g dose of emetic and poorly bioavailable compound for 90 days repeated dose toxicity studies in dog
Expediting early development through innovative precision capsule filling technology
Systematic formulation design - shorten development cost & time
Gastro Retentive Dosage Form
Developing a methodology for In situ perfusion based combined tissue distribution and toxicity evaluation study
Fixed Dose Combination Formulation
Development of quick quantification method for muscle injury recovery evaluation in thermal injury mice model
Designing a novel methodology for the development of a macrocyclic peptide molecule for both formulation development and pre-clinical studies
Advancing a target molecule from in vitro studies to clinical supply: An innovative scientific solution
Mitigating the manufacturing challenge of a New Chemical Entity comprising peptidomimetic molecule in order to achieve the desired scale-up
How the re-designed synthesis of a complex carbohydrate can reduce cycle time
Low yield challenges of a typical reaction
Product development in a challenging IP landscape
Mitigating technical challenges and cost impacts by improved process design
Route scouting for an enantiomerically enriched Isoflavone
PK properties of a compound and study its effect on animal (dog) model
Technology meets sustainability - How a complex API development process goes green
Building successful long-term partnerships with CDMOs from early drug discovery through commercialization
Accelerating Drug Discovery Through Innovative Partnerships
Evolution in Pharma Industry and Demand for Integrated CDMO
Peptide Development and Manufacturing
HPAPI Molecule from Development to Market
Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action.
Synthesis of Anti-covid Drug Nirmatrelvir Using Flow Chemistry
Simple and efficient synthesis of imidazoquinoxalines and spiroquinoxalinones via pictect-spengler reaction using Wang resin, Synthetic Communications
Polycyclic Aromatic Compounds: A Simple and Efficient [(n-Bu3Sn)2MO4]n Catalyzed Synthesis of Quinazolinones and Dihydroquinazolinones
Wang-OSO 3 H catalyzed green synthesis of bioactive isoindolo[2,1- a ]quinazoline-5,11–dione derivatives: An unexpected observation
Urea as an Ammonia Surrogate in the Hantzsch’s Synthesis of Polyhydroquinolines / 1,4-dihydropyridines under Green Reaction Conditions
Ultrasound assisted rapid synthesis of mefenamic acid based indole derivatives under ligand free Cu-catalysis: Their pharmacological evaluation
Base mediated spirocyclization of quinazoline: one-step synthesis of spiro-isoindolinone dihydroquinazolinones
Dhananjaya, G., AV Dhanunjaya Rao, Kazi Amirul Hossain, Venkateswara Rao Anna, and Manojit Pal. "In silico studies and β-cyclodextrin mediated neutral synthesis of 4-oxo-4, 5, 6, 7-tetrahydroindoles of potential biological interest." Tetrahedron Letters 6
Formal synthesis of Cladospolide C & epi-Cladospolide C using R- (þ)-g-valerolactone as a chiral synthon
Lipoplex-based therapeutics for effective oligonucleotide delivery: a compendious review
Amberlite-15 promoted an unprecedented aza Michael rearrangement for one pot synthesis of dihydroquinazolinone compounds
A convergent approach towards the synthesis of the 2-alkylsubstituted tetrahydroquinoline alkaloid ()-cuspareine
A diastereoselective synthesis of boceprevir's gem-dimethyl bicyclic [3.1.0] proline intermediate from an insecticide ingredient ciscypermethric acid
Synthesis of (+)-Patulolide C Using R-(+)-g-Valerolactone as a Chiral Synthon.
Novel highly selective peroxisome proliferator-activated receptor d (PPARd) modulators with pharmacokinetic properties suitable for once-daily oral dosing
A cascade reaction for the new and direct synthesis of indolofuroquinoxalines
Synthesis of 2-hydroxy-3-alkyl-2-phenyl-2,3- dihydroquinazolin-4(1H)-one via molybdenum hexacarbonyl mediated CO gas- and ligand free carbonylative reactions
An efficient and convenient protocol for the synthesis of tetracyclic isoindolo[1,2-a]quinazoline derivatives
A concise stereoselective synthesis of (+)-1-deoxy-6-epicastanospermine
A Simple Approach for the Synthesis of Fused Quinazoline-Based Tetracyclic Compounds via a Multicomponent Reaction Strategy
Stereoselective synthesis of (R)-() and (S)-(+)-phoracantholide I from (R)-(+)-c-valerolactone
Concise and highly stereoselective syntheses of D-fagomine and 2-epi-fagomine
A new strategy for accessing (S)-1-(furan-2-yl)pent-4-en-1-ol: a key precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins
FeF3-catalyzed MCR in PEG-400: ultrasound assisted synthesis of N-substituted 2- aminopyridines
Development of a Chemoenzymatic Process for Dehydroepiandrosterone Acetate Synthesis
Discovery of (R,E)‑N‑(7-Chloro-1-(1-[4-(dimethylamino)but-2- enoyl]azepan-3-yl)‑1H‑benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Muta...
A metal catalyst-free and one-pot synthesis of (3,4- dihydro-2H-benzo[b][1,4]oxazin-2-yl)methanol derivatives in water
An efficient one pot synthesis of 2-amino quinazolin-4(3H)-one derivative via MCR strategy
Sulfonic acid functionalized Wang resin (Wang-OSO3H) as polymeric acidic catalyst for the eco-friendly synthesis of 2,3-dihydroquinazolin-4(1H)-ones
A short diastereoselective synthesis of cis-(2S,4S) and cis-(2R,4R)-4- hydroxyprolines
A greener approach towards double heteroarylation of N, O and S nucleophiles: synthesis of bioactive polynuclear fused Nheteroarenes
Diastereoselective total synthesis of piperidine alkaloids: (2R,5R)- 5-hydroxyhomopipecolic acid and (2R,5R,8R)-5-hydroxysedamine
Diversity oriented concise asymmetric synthesis of azasugars: a facile access to L-2,3-trans-3,4-cis-dihydroxyproline and (3S,5S)-3,4,5-trihydroxypiperidine
Discovery of O-(3-carbamimidoylphenyl)-L-serine amides as matriptase inhibitors using a fragment-linking approach
Discovery of 1H-pyrazolo[3,4-b]pyridines as potent dual orexin receptor antagonists (DORAs)
A simple access to N-(un)substituted isoquinolin1(2H)-ones: unusual formation of regioisomeric isoquinolin-1(4H)-ones
Reactions of salicylaldehydes with activated terminal alkynes in aqueous media: synthesis of 3- substituted 4-hydroxy chromenes as potential cytotoxic agents
An oxidative amidation and heterocyclization approach for the synthesis of β-carbolines and dihydroeudistomin Y
Synthesis of tetrahedral diarylheptanoid ent-diospongin A and epimer-diospongin B by employing Julia–Kocienski olefination
Synthesis of tetrahedral diarylheptanoid ent-diospongin A and epimer-diospongin B by employing Julia–Kocienski olefination
Applications of Gage Reproducibility & Repeatability (GRR): Understanding and Quantifying the Effect of Variations from Different Sources on a Robust Process Development
Effect of Aqueous Polyethylene Glycol on 1,3-Dipolar Cycloaddition of Benzoylnitromethane/Ethyl 2-Nitroacetate with Dipolarophiles: Green Synthesis of Isoxazoles and Isoxazolines
3‑Alkoxy-pyrrolo[1,2‑b]pyrazolines as Selective Androgen Receptor Modulators with Ideal Physicochemical Properties for Transdermal Administration
Optimization of Spray Drying Process using Central Composite Design (CCD)
Formulation and Evaluation of Controlled Porosity Osmotic Drug Delivery System of Metoprolol Succinate
Synthesis of enantiomerically pure N-(2,3-dihydroxypropyl)arylamides via oxidative esterification
Cu-catalyzed coupling-cyclization in PEG 400 under ultrasound: a highly selective and greener approach towards isocoumarins
Diastereoselective total synthesis of 3,6-disubstituted piperidine alkaloids, (3R,6S)-epi-pseudoconhydrine and (3R,6R)-pseudoconhydrine
Identification of a Novel Series of Orexin Receptor Antagonists with a Distinct Effect on Sleep Architecture for the Treatment of Insomnia
Construction of a six-membered fused N-heterocyclic ring via a new 3-component reaction: synthesis of (pyrazolo)pyrimidines/pyridinesw
Construction of a quinoline ring via a 3-component reaction in water: crystal structure analysis and H-bonding patterns of a 2-aryl quinoline
An Efficient and Practical Synthesis of Aryl and Hetaryl a-Keto Esters
Synthesis of Isoquinoline Alkaloids via Oxidative Amidation–Bischler– Napieralski Reaction
Iodine catalyzed four-component reaction: a straightforward one-pot synthesis of functionalized pyrroles under metal-free conditions
N-heterocyclic carbene-mediated hydroacylation–Sonogashira/Heck/Suzuki coupling in a single pot: A new cascade reaction
Synthesis of novel 5-alkyl/aryl/heteroaryl substituted diethyl 3,4-dihydro-2H-pyrrole-4,4-dicarboxylates by aziridine ring expansion of 2-[(aziridin-1-yl)-1-alkyl/ aryl/heteroaryl-methylene]malonic acid diethyl esters
Yb(OTf)3 catalyzed new cascade reaction: a facile assembly of fused quinazolinones
Transition metal mediated construction of pyrrole ring on 2,3-dihydroquinolin-4(1H)-one: synthesis and pharmacological evaluation of novel tricyclic heteroarenes
A Concise and Cascade Synthesis of Batracylin and Substituted Isoindolo- [1,2-b]quinazolin-12(10H)-ones
A Concise and Convergent Synthesis of Luotonin B and E
Design and Development of a Fixed Dose Combination (FDC) of Delayed-Extended Release Niacin and a Flushing Modulator For Sequential Release
Optimization of formulation and process variable of nanosuspension: An industrial perspective
A highly effective synthesis of 2-alkynyl-7-azaindoles: Pd/C-mediated alkynylation of heteroaryl halides in water
Revisiting the reaction of b-chloroacroleins with 2-aminophenol: a new observation
Tandem versus single C–C bond forming reaction under palladium–copper catalysis: regioselective synthesis of a-pyrones fused with thiophene
Palladium-mediated synthesis of 5-substituted 4-alkynylthieno[2,3-c]pyran-7-onesq
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