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Accelerating Drug Discovery Through Innovative Partnerships Accelerating Drug Discovery Through Innovative Partnerships

Accelerating Drug Discovery Through Innovative Partnerships

Genomics plays a vital role in identifying which gene is associated with a specific disease. A gene called CNOT1 is for example known for it's effect on brain development and for impairing memory and learning. Despite the great promise genomics provides in understanding the disease, genes are not the best drug targets.

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Why Aurigene Services?

18 years of expertise

Experience gained from 100+ discovery programmes

World-class infrastructure

Track record of delivering 8+ IND candidates

Flexible working models

Quick turnaround time

Capabilities to apply multiple modalities

Seamless integration capabilities with Biology as well as CDMO services

Integrated project management

Expertise in various therapeutic modalities

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Aurigene Pharmaceutical Services Limited is a leading contract research, development and manufacturing organization (CDMO) providing end-to-end solutions. With a strong legacy of services in discovery, development and manufacturing we are ideally positioned to serve global pharma and specialty companies worldwide.

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Why meet us at CPHI Barcelona?

SEPTEMBER 04, 2023

Why meet us at CPHI Barcelona?

Discover the Opportunities: Visit Aurigene Pharmaceutical Services at CPHI BarcelonaThe Contract Research, Development and Manufacturing Organization (CRDMO) industry is a dynamic and rapidly evolving sector emerging as it plays a vital role in providing a wide range of services enabling drug companies to bring their products to market efficiently and effectively...

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Immuno Oncology - Therapies and Challenges

With more than 200 distinct cancer types recognized and steady increase in cancer incidence rates, the fight with cancer takes a new shape with each emerging decade. First was surgery, followed by radiotherapy and chemotherapy. The fourth one was targeted cancer therapeutics, also known as precision therapies. Precision therapies were established with the discove...

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Anti-Infective Drug Discovery

Objective & Challenges: Objective was to identify an optimized anti-bacterial lead molecule with in vivo efficacy in relevant infection models an acceptable safety profile, and a patentable series.      Challenge was to develop a more efficacious compound than the reference standard.Study design: Compounds were designed and synth...

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Alternate end-game strategies towards Nirmatrelvir synthesis: Defining a continuous flow process for the preparation of an anti-COVID drug

2023

Scalable alternate end-game strategies for the synthesis of the anti-COVID drug molecule Nirmatrelvir (1,PF-07321332) have been described. The first involves a direct synthesis of 1 via amidation of the carboxylic acid 7 (suitably activated as a mixed anhydride with either pivaloyl chloride or T3P) with the ...

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