• search
High Potent API Development Services High Potent API Development Services

High Potent API Development Services

We are committed to provide our clients with the safe, scalable and phase appropriate solutions for high potent drug development.

We offer highly potent small molecule development services for API and intermediates, operating from our development facility in Hyderabad, India. The development lab can handle molecules with OEL 0.1 µg/m3. We have a systematic approach to managing High potent APIs. which makes us one of the safest partners of choice for all your discovery needs. 

We can handle various potent molecules viz., heterocyclic, nucleosides, steroids and carbohydrates. 

Our approach for HPAPI handling

Speak to our experts

Dedicated HPAPI Labs

  • Self-equipped high potent chemical development lab with fume hoods (with negative pressure), barrier isolation, balance connected with isolator
  • Multi-purpose solids handling suites
  • High potent analytical labs with dedicated equipment connected with pass box
  • Biometric access control system
  • Capable to take up the development of HPAPI/Intermediates with OEL of 0.1µg/m³
  • Man-material entry and exit are separated to avoid contamination
  • Mist shower facility available for exit

Dedicated High Potent Analytical Lab

  • HPLC instrument with UV, DAD and CAD detectors
  • Gas chromatography with ALS and headspace injectors
  • Analytical balance (placed in Xpert filtered balance system)
  • pH meter
  • Ultrasound sonicator and rotary shaker
  • Zeta sizer
  • Isolator with HEPA cartridge for closed handling of the HPAI compounds
  • Pass box for sample transfer and atmos bag
  • Fume hood chemical handling and mobile phase preparations

Why Aurigene Pharmaceutical Services?

Integrated development and manufacturing

Dedicated analytical lab

Well-experienced team

Legacy of having developed and manufactured complex high potent products

Virtual Tour

Application and Manufacturing of High Potent Active Pharmaceutical Ingredient (HPAPI)

Application and Manufacturing of High Potent Active Pharmaceutical Ingredient (HPAPI)

High Potent Active Pharmaceutical Ingredient (HPAPIs) are majorly used to treat oncology-related conditions. Usually, a compound is considered high-potent when the operational exposure limit is below 10 µg/m3 of air as an 8-hour time-weighted average. High Potent drugs can be administrated through oral, injection or topical route depending on the source of the d...

Read More

HPAPI Development at a Glance

The pharmaceutical industry's journey to improve patients' health has enhanced the number of more effective HPAPIs (High Potent Active Pharmaceutical Ingredient) in development pipelines. Traditionally, HPAPIs were exclusively concomitant with oncology therapeutics. ...

Read More

High Potent API (HPAPI) Manufacturing Services

Aurigene Pharmaceutical Services has experience, expertise and infrastructure to develop and manufacture oncology drug candidates including HPAPI ...

Read More

Delivering 3 g dose of emetic and poorly bioavailable compound for 90 days repeated dose toxicity studies in dog

Background: Develop oral liquid dosage form of an IND candidate (small molecule) suitable for chronic toxicology studies in dogs. Must meet required systemic exposure and shall be dose proportional. Developed vehicle or used excipients shall be safe for chronic preclinical toxicology studies in dog. Challenges: Conventional suspension in dog resulted in low oral ...

Read More

Construction of a quinoline ring via a 3-component reaction in water: crystal structure analysis and H-bonding patterns of a 2-aryl quinoline


Montmorillonite K-10 mediated green and one-pot synthesis of 2-substituted quinolines has been accomplished via a 3-component reaction of aniline, aldehydes and ethyl 3,3- diethoxypropionate in the presence of air oxygen in water. The crystal structure analysis and H-bonding patterns of one compound prepared are presented. ...

Read More
View All

You are about to leave Aurigene Pharmaceutical Services and affiliates website. Aurigene Pharmaceutical Services assumes no responsibility for the information presented on the external website or any further links from such sites. These links are presented to you only as a convenience, and the inclusion of any link does not imply endorsement by Aurigene Pharmaceutical Services.

If you wish to continue to this external website, click Proceed.