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Biotherapeutics Discovery Infrastructure Biotherapeutics Discovery Infrastructure

Biotherapeutics Discovery Infrastructure

High-quality large molecule discovery services supported by cutting-edge facilities with a focus on scientific innovation.

Aurigene Pharmaceutical services is rapidly positioning itself to provide high-quality and high-value large molecule discovery services in traditional and advanced drug modalities. We have capabilities for ‘Target to Preclinical Proof-of-Concept’. We provide wide range of large molecule discovery services from our R and D center in Hyderabad. Our R and D site is US FDA inspected. Our infrastructure is well-equipped with :

BSLII compliant labs Spectrophotometer Flow cytometer Mass Spectrometer (Agilent 6545 Q-TOF))
Analytical HPLC FPLCs (AKTA) SPR-BIAcore T200 Automated western (Simple JESS)
Automated liquid handler (Bravo) Lab scale LNP formulation set-up for mRNA Real-Time PCR (96 and 384 well plate) Gel documentation systems
Benchtop fermenter for yeast and E. coli Static incubators and shakers Multimode plate readers (Victor & Envision) Tape station
Preparatory ultracentrifuge Cell disruptor/French press Independent cell culture suites with microscope, liquid nitrogen storage, biosafety cabinets, static and shaker CO 2 incubators, Centrifuges. 

We adhere to strong data integrity and traceability framework which is embedded in our SOPs and IT systems. We have daily automatic backups for all generated data.

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CDMO white paper

Advancement in personalized medicine and how the CRDMO industry is part of the solution

Personalized medicine is transforming the healthcare landscape by customizing treatment plans to individual patients’ unique genetic, clinical and environmental characteristics. These are effective and less invasive treatments for a wide range of conditions. Contract Research, Development and Manufacturing Organizations (CRDMOs) play an important role in enabli...

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Anti-infective drug discovery

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Objective & Challenges: Objective was to identify an optimized anti-bacterial lead molecule with in vivo efficacy in relevant infection models an acceptable safety profile, and a patentable series.      Challenge was to develop a more efficacious compound than the reference standard.Study design: Compounds were designed and synth...

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Bromelain is a complex natural mixture of proteolytic enzymes derived from pineapple (Ananas cosmosus), which has good therapeutic properties. Bromelain can be found in all tissues of pineapple plants, including the stem, fruit, and leaves. Bromelain plays an important role in the treatment of many diseases such as soft tissue inflammation and edema, deep derma, ...

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