A successful IDD program at Aurigene involves the participation of different domains like Medicinal Chemistry, Biochemistry, Cell & Molecular Biology, CADD, Analytical Chemistry, DMPK, Pharmacology, Safety and Toxicology, Scale-up & Process Development, Intellectual Property Management and Project Management. Amalgamation of 600+ highly skilled scientists in discovery team and state-of-the-art infrastructure at our Hyderabad and Bangalore sites, has resulted in successful delivery of many IND candidates. Our service is not limited to pharma and biotech companies, but also extend to animal health and crop science sectors.
We are flexible in our approach and offer a variety of business models including FTE & FFS mode of collaboration. In addition to the end-to-end IDD programs, we also offer a variety of “combination” packages to choose from, where our collaborators could select based on their unique requirements. Aurigene provides conducive environment for scientific innovation, which has resulted in several IND filings and a plethora of peer reviewed literature published in journals of international repute. We also bring with us a track record of solving complex challenges, using newer chemical modalities like peptides, PROTACs, lipids and Oligonucleotides.
18 years’ experience in drug discovery
Various customer models
65+ Integrated Drug Discovery projects delivered
Speed: Our average candidate nomination time is 24-28 months
Capabilities to apply multiple modalities
Seamless integration into development stages
Integrated project management
We understand that clear communication is essential to successful collaborations, and that's why we have a dedicated team that is always ready to help you. Whether you have questions about our services, want to discuss a potential partnership, or simply want to learn more about our company, we're here to help.
Our team of experts is dedicated to providing personalised solutions tailored to your unique needs. So, please don't hesitate to reach out to us. We look forward to hearing from you and helping you achieve your business goals.
An effective anti-tumor immune response in human is marked by presence of T cells reactive against neoantigens. Neoantigens are HLA-bound unique peptides arise from tumor-specific somatic mutations. Neoantigens are highly immunogenic because they are not present in normal tissues and hence bypass central thymic tolerance. The success of immune checkpoint blockade...
Read MoreGenomics plays a vital role in identifying which gene is associated with a specific disease. A gene called CNOT1 is for example known for it's effect on brain development and for impairing memory and learning. Despite the great promise genomics provides in understanding the disease, genes are not the best drug targets....
Read MoreBacked by our strong chemistry, we enable “Finger-print” protein structure and functional characterization for proteins from naked proteins to hyperglycosylated or derivatized proteins. ...
Read MoreBackground: Develop oral liquid dosage form of an IND candidate (small molecule) suitable for chronic toxicology studies in rats. Must meet required systemic exposure and shall be dose proportional. Developed vehicle or used excipients shall be safe for chronic preclinical toxicology studies. Challenges: Low oral bioavailability Practically insoluble in bio relev...
Read More2012
A conceptually new three-component reaction was developed to construct a six-membered fused N-heterocyclic ring affording (pyrazolo)pyrimidines/pyridines as potential inhibitors of PDE4. The reaction is catalyzed by triflic acid in acetic acid in the presence of aerial oxygen. ...
Read More2005
Drug Delivery System (DDS) has been used successfully in the past few decades to cure illnesses and enhance health because of its improved systemic circulation and ability to regulate the drug's pharmacological action. As pharmacology and pharmacokinetics advanced, the idea of controlled release emerged, demonstrating the significance of drug release in assessing...
Read More2005
Proteolysis-targeting chimera (PROTACs) represents a promising modality that has gained significant attention for cancer treatment. Using PROTAC technology, we synthesized novel structurally modified paullone-based PROTACs using Cereblon (CRBN) and Von Hippel–Lindau (VHL) E3 ligands....
Read More2005
Bromelain is a complex natural mixture of proteolytic enzymes derived from pineapple (Ananas cosmosus), which has good therapeutic properties. Bromelain can be found in all tissues of pineapple plants, including the stem, fruit, and leaves. Bromelain plays an important role in the treatment of many diseases such as soft tissue inflammation and edema, deep derma, ...
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