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Biotherapeutics Discovery Services Biotherapeutics Discovery Services

Biotherapeutics Discovery Services

We offer services across a wide range of therapeutic modalities or drug classes, supported by our disease and target area expertise.

We provide a wide range of discovery services for large molecules and Cell & Gene Therapy (CGT) from our state-of-the-art facility located in Hyderabad, India. At the core of our large molecule discovery services is a talented team of scientists experienced in the design and delivery of a range of advanced therapeutic modalities such as:  

Monoclonal Antibody (mAb) Antibody Drug Conjugates (ADC) Bi-specific antibodies Protein therapeutics mRNA Viral vectors Cell therapeutics 

We establish and adopt innovative technology platforms for faster solutions to complex problems throughout the biologics value chain.

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Why Aurigene Pharmaceutical Services?

State-of-the-art facilities

Multiple technology platforms

Analytical assessment to ensure safety and quality

Strong framework of data integrity and traceability

Regulatory audits & compliance as per global standards

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Neoantigen Specific T cells For Cancer Immunotherapy

Neoantigen Specific T cells For Cancer Immunotherapy

An effective anti-tumor immune response in human is marked by presence of T cells reactive against neoantigens. Neoantigens are HLA-bound unique peptides arise from tumor-specific somatic mutations. Neoantigens are highly immunogenic because they are not present in normal tissues and hence bypass central thymic tolerance. The success of immune checkpoint blockade...

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Peptide Development and Manufacturing

Peptides are short chains of amino acids that are linked by peptide bonds. Several peptides linked together are called polypeptides. A protein contains one or more polypeptides. Therefore, proteins are long chains of amino acids held together by peptide bonds....

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Biologics Process Development Services

Our strength is built on a deep understanding of cell culture, protein chemistry and an integrated analytics platform enabling a robust, scalable and controlled process. ...

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Systematic formulation design - shorten development cost & time

Project Challenge: Existing formulation (lower strength - 50 mg) was manufactured using direct compression process. This formulation posed poor powder flow and content uniformity issues during scale-up. Development of new strength 150 mg without any process issues was a challenge. Solution design: Preliminary pre-formulation, stress study and PSD impact assessmen...

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A metal catalyst-free and one-pot synthesis of (3,4- dihydro-2H-benzo[b][1,4]oxazin-2-yl)methanol derivatives in water


A robust and metal catalyst-free method has been developed for the general and green synthesis of racemic (3,4-dihydro-2H-benzo[b][1,4] oxazin-2-yl)methanol derivatives. This simple, mild and practical method involves the reaction of 2-aminophenols with ()-epichlorohydrin in the presence of NaOH in water at room temperature. The reaction features high regioselec...

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