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Process and Powder Safety Assessment

Process and Powder Safety Assessment

Risk-free safety assured sustainable processes.

We are committed to the highest standards of Environment, Health and Safety. We follow a very robust and systematic approach to ensure risk assessment and safety studies. We also evaluate alternative options to adopt safer processes throughout our research from development to manufacturing and safe handling of powders.

We offer process and powder safety assessment studies prior to manufacturing, irrespective of the phase of the molecule.

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Safety Assessment using Literature and Database

  • Review of the synthetic scheme for the potential hazards’ functionalities and gaseous by-products
  • Assessing the hazardous nature of reagents or solvents used for the conversions by referring to the available data such as material safety data sheet (MSDS) and Brethrick's handbook of reactive chemical hazards. Review of the reaction parameters such as temperature and pressure

Safety Assessment : Screening Tests and Instruments

  • Basic safety screening tests which include:
    • Differential scanning calorimetry (DSC) for reaction masses, organic layers, mixtures, intermediates, etc.
    • Thermal Screening Unit (TSU) studies
    • Reaction Calorimetry (RC1mx)
    • Accelerating Rate Calorimetry (ARC)
  • Powder safety studies which include:
    • Minimum ignition energy (MIE)
    • Bulk powder resistivity test
    • BAM Fall Hammer test
    • Burning behavior
    • Dust explosion

Why Aurigene Pharmaceutical Services?

Safety evaluation labs with infrastructure to support calorimetry, thermal screening and powder safety

Stringent SOPs for risk evaluation and stage wise risk assessment and safety reports

Assessed 500+ compounds

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