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Early Phase Formulation Development Services Early Phase Formulation Development Services

Early Phase Formulation Development Services

Our early-phase formulation development services are tailored to address specific drug delivery challenges.

Our early-phase formulation development services help to resolve drug delivery challenges encountered at both preclinical and clinical development stages of small molecules and peptides. We offer specific solutions to your preformulation and formulation needs through customized development strategies and designs.    

Our expert team of scientists have successfully delivered projects in wide range of areas like incomplete dissolution, low solubility, low oral bioavailability and targeted drug delivery through in-depth molecular characterization, various solubilization and enabling technologies.

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Our Services for Preclinical Formulation Development Include

Many hits and lead NCEs get shelved from pharmacological and toxicity screening despite high potency because of poor bioavailability or suboptimal formulation. As a leading CDMO company, we have more than a decade of experience in helping our clients overcome these challenges by enabling preclinical and GLP toxicology studies.

Our preclinical formulation development approach considers but is not limited to

Oral formulation

  • Suspension
  • Solution
  • Solid dispersion
  • Enteric solid dispersion
  • Lipid based delivery (Emulsion/SMEDDS)
  • Micro/Nano-suspension

Parenteral formulation

  • Solution
  • Lyophilization
  • Emulsion
  • Nano-suspension

Oral Bioavailability Enhancement Services Include

Our formulation team has the expertise in troubleshooting complex problems by banking various oral bioavailability enhancement strategies to accelerate your drug discovery program to the next phase.

Formulation development strategies are:

Solubilization strategies

  • Micellar solubilization
  • Complexation
  • pH modification/buffering
  • Cosolvents
  • Anti-precipitating agents

Enabling technologies

  • Solid dispersions
    • Spray drying
    • Rota-evaporation
    • Spray granulation technology
    • Hot melt extrusion
  • Particle size reduction
    • Micronization (Air-jet mill)
    • Nanosizing
  • Lipid-based drug delivery systems
    • Emulsion
    • SEDDS/SMEDDS
    • Lipid formulation filled in Soft gelatin capsules
Early Phase Formulation Development

Our data-driven approach enables our partners to advance candidates and select the most optimal formulation for a specific drug development phase.

Why Aurigene Pharmaceutical Services?

Services from early formulation to clinical manufacturing

Experience with advanced formulation technologies

Integration with biology services for in vitro and in vivo studies

Global accreditations

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Connect with our scientific experts for your drug discovery, development, and manufacturing needs

We understand that clear communication is essential to successful collaborations, and that's why we have a dedicated team that is always ready to help you. Whether you have questions about our services, want to discuss a potential partnership, or simply want to learn more about our company, we're here to help.

Our team of experts is dedicated to providing personalised solutions tailored to your unique needs. So, please don't hesitate to reach out to us. We look forward to hearing from you and helping you achieve your business goals.

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