Research Cell Bank Service Page

Aurigene applies a structured screening framework to evaluate candidate clones before research cell banking. This stage focuses on identifying cell populations that demonstrate suitable productivity, growth behavior, and expression stability under controlled culture conditions.

• Clone isolation and screening workflows
• Performance evaluation in fed batch shake flask systems
• Controlled culture environments for temperature, CO₂, and humidity
• Assessment of productivity and growth characteristics
• Evaluation of expression stability across cell generations

Once suitable clones are selected, research cell banks are prepared through controlled cryopreservation workflows designed to maintain cell viability and reproducibility across development studies. The infrastructure also supports secure storage and organized management of cryovial inventories.

• Research cell bank preparation and cryopreservation
• Controlled freezing workflows for reliable recovery of banked cells
• Liquid nitrogen storage infrastructure with capacity exceeding 30,000 cryovials
• Inventory management systems for traceable storage and retrieval

Research cell banks established within this platform serve as consistent starting material for multiple development activities. By preserving a stable cell source early in development, research teams can improve comparability across experiments and support smoother progression of biologics programs.

• Starting material for upstream process optimization
• Support for analytical method development studies
• Material for formulation development and stability evaluation
• Support for process scale up and development studies
• Applicability across monoclonal antibodies, bispecific antibodies, recombinant proteins, and related biologics

Research cell banking activities operate within a digitally enabled quality environment that supports traceability, documentation control, and consistent handling of research materials throughout development programs.

• Document management systems
• Training management and personnel qualification tracking
• Validation tracking and controlled change management
• Incident management and deviation tracking
• Electronic laboratory notebook documentation
• Controlled access systems and automated data backup
• Structured governance processes supporting data integrity

• Pool generation and characterization
• Monoclone generation and screening
• Clone performance evaluation in fed batch systems
• Stability analysis of selected clones
• Research cell bank preparation and cryopreservation
• Liquid nitrogen storage and inventory management
• Integration with upstream development and analytical workflows

Automated monoclonal generation and clone evaluation workflows help identify productive and stable clones suitable for early development programs.

Large-scale liquid nitrogen storage capacity supports reliable preservation and availability of research cell banks.

Aurigene’s digital systems support documentation control, data integrity, and operational transparency across development activities.