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Aurigene Pharmaceutical Services Limited is a leading contract research, development, and manufacturing organization (CRO/CDMO) and a long-term partner providing end-to-end solutions thereby accelerating innovation. With a strong legacy of services in discovery chemistry, discovery biology, development and manufacturing we are ideally positioned to serve global pharma and specialty companies worldwide by providing truly integrated services.

We handle both small molecule and large-molecule services across various complex technology platforms and niche technologies. We have access to FDA-inspected dedicated R and D centers in India and cGMP sites across India, UK and Mexico. Beyond science, our operations are rooted in the fundamental principles of compliance, information security, quality and sustainability.

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Leading CRO/CDMO and a long-term partner

We are uniquely positioned to serve our customers and accelerate their journey to the clinic from discovery to commercialization by nurturing long-term partnerships.

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JUNE 28, 2022

Neoantigen specific T cells for cellular cancer immunotherapy

An effective anti-tumor immune response in human is marked by presence of T cells reactive against neoantigens. Neoantigens are HLA-bound unique peptides arise from tumor-specific somatic mutations. Neoantigens are highly immunogenic because they are not present in normal tissues and hence bypass central thymic tolerance. The success of immune checkpoin...

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Building successful long-term partnerships with CDMOs from early drug discovery through commercialization

Building successful long-term partnerships with CDMOs from early drug discovery through commercialization Maximizing efficiency in drug research, development, and manufacturing is crucial for turning new innovations into therapeutic and financial benefits. Over the past couple of decades, pharmaceutical companies have increasingly turned to contr...

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Technology meets sustainability - How a complex API development process goes green

We are always looking for ways to enhance the sustainability of our products and services. Our team successfully developed a scalable manufacturing process for the API product of one of our Biotech clients using eco-friendly manufacturing technologies. Read the case study to learn more. ...

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Alternate end-game strategies towards Nirmatrelvir synthesis: Defining a continuous flow process for the preparation of an anti-COVID drug

2023

Scalable alternate end-game strategies for the synthesis of the anti-COVID drug molecule Nirmatrelvir (1,PF-07321332) have been described. The first involves a direct synthesis of 1 via amidation of the carboxylic acid 7 (suitably activated as a mixed anhydride with either pivaloyl chloride or T3P) with the ...

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