At Aurigene, we provide end-to-end antibody discovery solutions that power the development of traditional monoclonal antibodies as well as advanced therapeutic formats including bispecifics (bsAbs), multispecifics, antibody-drug conjugates (ADCs), and CAR T-cell therapies. Leveraging a suite of proprietary platforms, screening tiers, fit-for-purpose tools, and scientific expertise, our services are designed to meet the diverse and evolving needs of drug developers.
Key Technologies & Proprietary Platforms
Our key technologies and proprietary platforms include:
- B-CAD: B-cell cultur platform for high-affinity, high-diversity, and high-throughput screening
- HyFusn: Hybridoma generation with high-efficiency fusion techniques
- Display Platforms: Phage and yeast display libraries, including synthetic nanobody library
- Antibody Engineering: Humanization, affinity maturation, Fc engineering, in silico developability, conjugation and Reformatting in bispecific/multispecific/CAR designs
- Comprehensive Screening Suite: Flow cytometry, ELISA, Octet, SPR, and fit-for-purpose functional assays
Workflow Overview
Our integrated discovery workflow includes:
- Antigen Design & Immunization
- Hybridoma and B-cell Platforms
- Fit-for-purpose screening & Characterization
- Antibody Engineering & Optimization
- Functional Evaluation & Candidate Selection
Why Choose Aurigene for Antibody Discovery?
State-of-the-art, AAALAC-accredited animal facilities
Proprietary high-throughput platforms for accelerated timelines
Deep expertise indiscovering high affinity antibodies
Customizable programs for diverse therapeutic endpoints
Seamless integration from immunogen design to final candidate delivery
Virtual Tour
Hyderabad R and D Center
Bangalore R and D Center
Connect with our scientific experts for your drug discovery, development, and manufacturing needs
We understand that clear communication is essential to successful collaborations, and that's why we have a dedicated team that is always ready to help you. Whether you have questions about our services, want to discuss a potential partnership, or simply want to learn more about our company, we're here to help.
Our team of experts is dedicated to providing personalised solutions tailored to your unique needs. So, please don't hesitate to reach out to us. We look forward to hearing from you and helping you achieve your business goals.
Learning Resources
The importance of business continuity planning in CRDMO industry
Both natural and unnatural catastrophic events inflict negative consequences due to the ever-increasing interconnectedness of the global economy. Those consequences are certain to last for longer duration. e.g.; The Covid-19 pandemic is still having a negative impact on the global economy. Maintaining continuity is critical for all businesses, but perhaps no othe...
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Evolution in Pharma Industry and Demand for Integrated CDMO
The pharma industry is evolving and a demand for integrated CDMOs, which can help accelerating innovations, is part of the evolution....
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cGMP Development and Manufacturing Services
Aurigene Pharmaceutical Services has a legacy of +20 years in developing and manufacturing compounds under cGMP. Our manufacturing plants are spread across 3 continents with facilities in India, UK, and Mexico. ...
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Systematic formulation design - shorten development cost & time
Project Challenge: Existing formulation (lower strength - 50 mg) was manufactured using direct compression process. This formulation posed poor powder flow and content uniformity issues during scale-up. Development of new strength 150 mg without any process issues was a challenge. Solution design: Preliminary pre-formulation, stress study and PSD impact assessmen...
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Synthesis of 2-hydroxy-3-alkyl-2-phenyl-2,3- dihydroquinazolin-4(1H)-one via molybdenum hexacarbonyl mediated CO gas- and ligand free carbonylative reactions
2016
Carbon monoxide gas and ligand-free conditions were developed for the synthesis of 2-hydroxy-3-alkyl-2-phenyl-2,3-dihydroquinazolin4(1H)-one via catalytic carbonylation with molybdenum hexacarbonyl as an efficient carbonylating agent for the three-component reaction of isatoic anhydride, amine, iodobenzene. Mo(CO)6 is a solid carbon monoxide source. The quinazoli...
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Development and assessment of a Bcs class II - SGLT2 (Sodium Glucose Cotransporter 2) inhibitor drug in the form of solid lipid Nanoparticles by selecting different lipids, co-surfactants, and manufacturing techniques
Drug Delivery System (DDS) has been used successfully in the past few decades to cure illnesses and enhance health because of its improved systemic circulation and ability to regulate the drug's pharmacological action. As pharmacology and pharmacokinetics advanced, the idea of controlled release emerged, demonstrating the significance of drug release in assessing...
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Development of novel paullone-based PROTACs as anticancer agents
Proteolysis-targeting chimera (PROTACs) represents a promising modality that has gained significant attention for cancer treatment. Using PROTAC technology, we synthesized novel structurally modified paullone-based PROTACs using Cereblon (CRBN) and Von Hippel–Lindau (VHL) E3 ligands....
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Development and verification of RP-HPLC method for the quantitative determination of Decitabine in tablet dosage formulation
Decitabine is an anti-cancer chemotherapy drug. This article describes method development and method verification of Assay of Decitabine in tablet formulation. A new, precise, rapid, accurate RP-HPLC method has been developed for the estimation of Decitabine in pharmaceutical tablets dosage form. After optimization the good chromatographic separation was achieved...
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