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Leading CDMO/CRO Company - Aurigene Pharmaceutical Services
A New Beginning, Built on Decades of Experience in Servicing the Outsourcing Needs of Innovator Pharma Companies.
Aurigene Pharmaceutical Services Limited is a leading contract research, development and manufacturing organization (CDMO) providing end-to-end solutions. With a strong legacy of services in discovery, development and manufacturing we are ideally positioned to serve global pharma and specialty companies worldwide.
Our endeavor is to help accelerate the journey from laboratory to market by providing access to our capabilities, knowledge and experience. Our team of highly qualified and experienced scientists and engineers backed by the state-of-the-art labs and manufacturing infrastructure, work relentlessly for the success of our clients.
Our end-to-end integrated services offerings range from discovery chemistry, discovery biology, custom development and manufacturing of clinical compounds to enable your IND/NDA fillings and commercial contract manufacturing. Our discovery and development services are offered from world-class R&D centers situated in India. This is supported by scale-up and commercial manufacturing facilities in India, UK, Mexico and the United States.
While accelerating the R&D programs of our clients, we keep sustainability, quality, environment, health and safety (EHS) at the forefront of everything we do.
Aurigene Pharmaceutical Services creates value for its clients through its services including:
Client Speak
“ I’m very satisfied with the chemistry work at APSL, collaborated both chemistry (FTE) and biology (FFS). Technical discussion, weekly updates and meetings were good.”
Testimonial By Biotech, US“APSL is very flexible in allocating FTEs and shipping compounds to the preferred destination. Updates on raw material, reports and LNBs are remarkable. Quick turn around time for solving problems using analytical techniques.”
Testimonial By Large Pharma, APAC“Based on the FFS experience with APSL, it increased the bandwidth from FFS to FTE business. The level of communication and transparency in communication was excellent. Project reports and weekly updates are prepared well and on time. ”
Testimonial By Biotech, US“Based on the pilot peptide program, we extended an FTE collaboration with Aurigene. The scientific team was excellent in communication and problem-solving. The management was proactive and ready to invest in capability and capacity building.”
Testimonial By Large pharma, US“Happy with the quality of product, productivity and problem-solving capacity. Proactive communication about shipments helped us to plan our studies efficiently. APSL is a one-stop-shop for our discovery and development needs.”
Testimonial By Large pharma, EU“Happy with the scientific team, hence restarted research collaboration. The team is very responsible, trustable, and reliable. All discovery services are under one roof.”
Testimonial By Biotech, USContact us
Resources
Advantages of PROTACs over traditional drugs
Proteolysis Targeting Chimera (PROTAC) can overcome most of the limitations of small molecule inhibitors, and they offer several advantages of the traditional concepts of drug discovery by targeted protein degradation. Their Mode of Action (MoA) suggests that a small molecule just needs a brief interaction with its target protein, leading to the los...
FEBRUARY 08, 2021 READ MORE
Application & Manufacturing of High Potent Active Pharmaceutical Ingredient (HPAPI)
High Potent Active Pharmaceutical Ingredient (HPAPIs) are majorly used to treat oncology-related conditions. Usually, a compound is considered high-potent when the operational exposure limit is below 10 µg/m3 of air as an 8-hour time-weighted average. High Potent drugs can be administrated through oral, injection or topical route depending on the s...
JANUARY 04, 2021 READ MORE
Application of mPEGs in Drug Discovery and Development
Methoxy Polyethylene Glycols (mPEGs) are increasingly being applied in drug discovery and drug development to enhance the deliverability and bioavailability of the drug, and to increase the serum half-life. Today, due to advancements in chemical processes and purification techniques it is possible to produce high-quality mPEGs. mPEGs in combinati...
JANUARY 04, 2021 READ MORE
Emerging Trends in Solid State Phase Peptide Synthesis
Peptides are short chains of amino acids that are linked by peptide bonds. Peptides are highly specific and offer improved toxicological profiles. Peptides are produced using one of three synthesis methods: Solid phase peptide synthesis, liquid phase pepide synthesis or a hybrid approach. Solid-phase peptide synthesis (SPPS) is one of the most commo...
FEBRUARY 23, 2021 READ MORE
Importance of Route Scouting in Chemical Development
Route Scouting is an essential step in the chemical development process for the manufacturing of a drug substance. When the compound passes the preclinical stage and reaches the development phase, the route of synthesis used in the drug discovery phase may not be feasible or be the optimum route of synthesis for large scale manufacturing. Proces...
FEBRUARY 05, 2021 READ MORE
Introduction to Protac Technology and Design Services
PROteolysis TArgeting Chimeras (PROTAC) are a series of hetero-bifunctional molecules that hijack the body’s natural disposal system to initiate selective degradation of the protein of interest (POI). They are generally bifunctional molecules that hijack the Ubiquitin Proteasome System (UPS) to achieve the total degradation of a disease-related ta...
FEBRUARY 08, 2021 READ MORE
Neoantigen Specific T cells For Cancer Immunotherapy
An effective anti-tumor immune response in human is marked by presence of T cells reactive against neoantigens. Neoantigens are HLA-bound unique peptides arise from tumor-specific somatic mutations. Neoantigens are highly immunogenic because they are not present in normal tissues and hence bypass central thymic tolerance. The success of immune checkpoin...
JUNE 28, 2022 READ MORE
Oligonucleotide as a novel class of therapeutic modality
Oligonucleotides as a therapeutic class is a revolutionary approach to discover new and important therapeutic agents for treating human diseases. RNA-based intervention at times works in cases where other modalities do not work. For example, it may help in treating inborn errors in metabolism, genetic disorders and rare Oligonucleotide therapeutics i...
JULY 02, 2021 READ MORE
Role of Peptide Synthesis Based Drugs
Amino acids, peptides and proteins play multiple roles in the normal functioning of the body. Group of amino acids between 2 to 50 are called peptides. They often act as hormones and play diverse roles in the normal biological processes in the human body such as metabolism, intercellular signaling and neurotransmission. Peptide synthesis based d...
JANUARY 04, 2021 READ MORE
The Importance of Carbohydrate Synthesized Drugs
There is an emerging trend in carbohydrates derivative drugs for therapeutic use. Naturally, Carbohydrate is broken down in the body to produce energy for various biological activities. Carbohydrates can be segmented into monosaccharides, polysaccharides, complex pentasaccharides, nucleosides, nucleotides, glycopeptides, iminosugars, carbocycli...
JANUARY 04, 2021 READ MORE
The influence of formulation development and its route of administration
Physicochemical properties of drug forecast its ADME chance, however, the formulation development strategy or dosage form is decided based on the bioavailability, commencement and duration of therapeutic response. An ideal strategy for formulation development should consider the dose of the drug, intended route of administration, anatomical and phys...
JANUARY 04, 2021 READ MORE
The Role of DMPK Studies in Drug Discovery
DMPK studies play a crucial role in drug discovery for optimizing the drug-like properties of compounds or drug molecules. They enable researchers to rank compounds based on favorable pharmacokinetic properties associated with absorption, distribution, clearance, elimination (ADME) and DDI potential. The in-vitro assays and in-vivo animal studies provid...
JANUARY 04, 2021 READ MORE
Accelerating Drug Discovery Through Innovative Partnerships
Genomics plays a vital role in identifying which gene is associated with a specific disease. A gene called CNOT1 is for example known for it's effect on brain development and for impairing memory and learning. Despite the great promise genomics provides in understanding the disease, genes are not the best drug targets. ...
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Evolution in Pharma Industry and Demand for Integrated CDMO
The pharma industry is evolving and a demand for integrated CDMOs, which can help accelerating innovations, is part of the evolution. ...
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HPAPI Development at a Glance
The pharmaceutical industry's journey to improve patients' health has enhanced the number of more effective HPAPIs (High Potent Active Pharmaceutical Ingredient) in development pipelines. Traditionally, HPAPIs were exclusively concomitant with oncology therapeutics. ...
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HPAPI Molecule from Development to Market
The global Highly Potent Active Pharmaceutical Ingredients (HPAPI) market is expected to reach USD 26.84 Billion by 2023 from USD 17.72 Billion in 2018, at a CAGR 8.7%. ...
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Peptide Development and Manufacturing
Peptides are short chains of amino acids that are linked by peptide bonds. Several peptides linked together are called polypeptides. A protein contains one or more polypeptides. Therefore, proteins are long chains of amino acids held together by peptide bonds. ...
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Biologics Formulation Development Services
Deep rooted in our fundamental understanding of protein chemistry, our formulation expertise spans a wide range of proteins such as – chemically derivatized proteins, receptor fusion proteins, hyperglycosylated proteins and monoclonal antibodies and fragments. ...
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Biologics Manufacturing Services
Our manufacturing services cater to both GMP and non-GMP manufacturing for pre-clinical development as well as GMP operation to support clinical or commercial needs for any recombinant proteins expressed in suspension mammalian culture or E. coli. ...
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Biologics Process Development Services
Our strength is built on a deep understanding of cell culture, protein chemistry and an integrated analytics platform enabling a robust, scalable and controlled process. ...
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Biologics Process Scale-up Services
Built on a solid platform of development and manufacturing scientist, we enable scale up doe both upstream and downstream processes. ...
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Cell Line Development
We enable development of stable and high yielding recombinant Mammalian and Microbial lines. ...
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cGMP Development and Manufacturing Services
Aurigene Pharmaceutical Services has a legacy of +20 years in developing and manufacturing compounds under cGMP. Our manufacturing plants are spread across 3 continents with facilities in India, UK, and Mexico. ...
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Custom Peptide Synthesis
Aurigene Pharmaceutical Services has decades of experience in providing services for peptide drug discovery, development and formulation manufacturing and is specialized in the synthesis of various types ...
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Discovery, Development and Manufacturing Services
Aurigene Pharmaceutical Services is a leading contract research, development and manufacturing organization which provides range of services to enable your IND/NDA filing ...
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Formulation Development Services
We offer end-to-end formulation development and manufacturing services such as pre-formulations, clinical development, clinical supplies and commercial manufacturing. ...
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High Potent API (HPAPI) Manufacturing Services
Aurigene Pharmaceutical Services has experience, expertise and infrastructure to develop and manufacture oncology drug candidates including HPAPI ...
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Methoxy Polyethylene Glycol (m-PEGs)
Aurigene Pharmaceutical Services is a leader in the synthesis of activated MethoxyPolyethyleneGlycol(m-PEGs), With a comprehensive product range and customized services. ...
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Physiochemical Characterization Services
Backed by our strong chemistry, we enable “Finger-print” protein structure and functional characterization for proteins from naked proteins to hyperglycosylated or derivatized proteins. ...
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