CACO-2 permeability assay help determine the absorption rate, which is the compound's bioavailability, and helps predict the absorption during in vivo studies. Our ADME services team determines the absorption of the New Chemical Entity (NCE) by dosing it on Colon Carcinoma Cells (CACO-2).
Our CACO-2 assay is a monolayer membrane that can be tailored to your requirements and meet regulatory requirements. We can also help our clients understand unidirectional and bi-direction permeability.
Assay | Analysis | Data turn around time |
Caco-2 permeability | LC-MS/MS | 5 days* |
*21 days are required for Caco-2 cell cultures
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