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Oligonucleotide Synthesis Services

At our state-of-the-art drug discovery facility for oligonucleotide synthesis, our team accelerates your early drug discovery. With years of experience in small molecules, we can design molecules, overcoming bioavailability issues, and devising a fast-forward approach for your oligo targets across therapeutic areas such as oncology, inflammation, and anti-bacterial, etc.

Our dedicated oligonucleotide platform helps to encapsulate oligonucleotide molecules for better bioavailability, and CADD trained team helps optimize the designed oligonucleotide along with primary assay iterations. We can Synthesis 10-40-mer oligonucleotide up to 1 gram scale. We can perform all standard modifications, with or without backbone modification, for which phosphoramidites are commercially available. We also have the capabilities of making any customized phosphoramidite in-house

Our Oligonucleotide synthesis services is backed by:

  • K&A H-16 automated DNA/RNA synthesizer
  • AKTA pure 25M FPLC purification system
  • Sartoflow smart TFF system for concentration and desalting
  • Martin Christ LSC plus lyophilizer with lyocube, benchtop tray lyophilizer
  • Agilent LCMS for oligonucleotide analysis
  • Implen N60 nano spectrophotometer

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Services Video

Webinar on "Therapeutic Oligonucleotides: A Path Breaking Modality"
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